SVEA Column Selection

PhaseCharacteristicsSuggested applicationsParticle typePore sizeCarbon loadingSurface areaPore volumeEnd-cappingUSP
pH rangeParticle sizes
C18 GoldGeneral first choice column. High hydrophobic retention.
Wide range of analytes. Excellent peak shape for acids
and bases. High carbon content. Withstands
temperatures up to 60 °C. Long life time. Widely used
for the separation of various medicines, foods and
Cephalosporins, preservatives, sunscreens, amoxicillin, nitrofuran,
amino acids, flavonoids, polycyclic aromatic hydrocarbons, carbamates,
coal phenols, aldonic acids, tropisetron, acetylsalicylic acid, ibuprofen,
base peptides, water-soluble vitamins, Chinese herbs (Eucommia),
chlorogenic acid, traditional Chinese medicine (astragalus), synthetic
dyes, queen bee acid, methylfurfural, dimethyl fumarate, synthetic
pigments, sodium cyclohexyl sulfamate, dehydroacetic acid, natamycin,
taurine, carnitine, benzopyrene, adenine, guanine, hypoxanthine,
nucleotides, Cefazolin, Ciprofloxacin Hydrochloride, Ethinyl Estradiol
Impurity, Nicotinamide, Artemether, Benzyl Alcohol, Ceftriaxone and
Sulbactam, Cholecalciferol, D-Panthenol, Vitamin E etc
Fully porous
type B silica
110 Å19%300 m²/g0.85 ml/gYesL10.9-103.5, 5 µm
C 18 OpalRecommended for high pH applications. Proprietary
coating ensures solely hydrophobic interactions. Better
peak shape for ionizable compounds. Withstand
temperatures up to 80 °C. Can be used in aqueous
conditions. Has advantages over C18 Gold in multicomponent analyses. Can be used for analysis of difficult
experiments, with good universality and high market
utilization rate.
Macrolide antibiotics such as azithromycin US European
Pharmacopoeia, azithromycin Chinese Pharmacopoeia system
applicability, roxithromycin, erythromycin, aminoglycoside, antibiotics
such as gentamicin, simvastatin, aflatoxin, natamycin, organic acids,
chalk, alkaloids, pigments, folic acid, benzoyl peroxide, ginsenosides,
irbesartan, anthocyanins, neurotransmitters, etc.
Fully porous
type B silica
110 Å14%300 m²/g0.85 ml/gYesL10.5-113.5, 5 µm
C8Similar selectivity for lipophilic compounds as C18 Gold.
Lower retention than C18 Gold. Slightly different
selectivity for ionized acids and bases compared to C18
Gold. Excellent peak shape for acids and bases. High
stability and longevity. Wide applicability - can be used
as the first choice for C8 columns.
Water-soluble organic acid, clozapine, cefuroxime sodium, organic
acid, dichlorophenol and other phenolic compounds, triclosan,
Paracetamol and Ibuprofen, etc.
Fully porous
type B silica
110 Å11%300 m²/g0.85 ml/gYesL71-93.5, 5 µm
C4Recommended for separation of large peptides and
proteins. Very low retention for lipophilic compounds.
Can also be run in HILIC-mode. The C4 column is
optimized for protein analysis with low adsorption and
high recovery.
Insulin, lactoferrin, liraglutide etc. Fully porous
type B silica
110 Å7%300 m²/g0.85 ml/gYesL261-83.5, 5 µm
PhHexOrthogonal chemistry for method development. Can be
used in aqueous conditions. Recommended for
separation of aromatics and/or polar analytes. Long life
Pseudoephedrine, carbamazepine, verapamil hydrochloride,
nicardipine hydrochloride, carbamate, Anagrelide Hydrochloride
Fully porous
type B silica
110 Å16%300 m²/g0.85 ml/gYesL112-83.5, 5 µm
PFPStrong retention of protic compounds and analytes with
high dipole moments. Strong π-interaction with electron
deficient aromatic rings. Recommended for very polar
Analysis of four subtypes of tocopherol (vitamin E), matrine, isomers.Fully porous
type B silica
110 Å11%300 m²/g0.85 ml/gYesL432-83.5, 5 µm
CyanoVery polar stationary phase. Strong dipole-dipole
interactions. Orthogonal phase in RPLC method
development. Recommended for HILIC and Normal
Phase. High stability and longevity.
Benzalkonium chloride, steroids, malic acid, fumaric acid, OndansetronFully porous
type B silica
110 Å7%300 m²/g0.85 ml/gYesL102-7.53.5, 5 µm
Core C18Core shell technology provides high separation and low
back pressures. Can be used in HPLC and UPLC. Excellent
base stability. Widely used in the field of rapid analysis of
food, drug and cosmetics
Flavonoids such as myricetin, quercetin, apigenin, baicalein, aflatoxin,
anthraquinone dyes such as alizarin, alfalfa, phenol, tea polyphenols,
caffeine, gallic acid, dinitrobenzene, bisphenol A, tetracyclines,
ethambutol hydrochloride, clenbuterol, salbutamol, ginsenosides,
amoxicillin, clavulanate potassium, atenolol, nifedipine, nitridipine, H2
receptor blocker (fumetidine, cimetidine, ranitidine), corticosteroids
(prednisone, cortisone, hydrocortisone, dehydrocortisol), ethinyl
estradiol, estrogen ketone, p-aminoacetophenone, chloroquine, oleic
acid, fluridic acid, hydroquinone, quinolone (2-hydroxyquinoline),
sulfonamides, tetracyclines (chlortetracycline, oxytetracycline,
doxycycline hydrochloride), chloramphenicol , malachite green, etc.
type B silica
80-100 Å6-8%110-150 m²/g0.25-0.32 ml/gProprietaryL11-102.6 µm
Core PhHexOrthogonal chemistry combined with core shell
technology to provide high separation and low back
pressures. Can be used in aqueous conditions.
Recommended for separation of aromatics and/or polar
analytes. Can be used in HPLC and UPLC.
Pseudoephedrine, carbamazepineCoreshell
type B silica
80-100 Å4-5%110-150 m²/g0.25-0.32 ml/gProprietaryL111.5-92.6 µm